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General laboratory findings in clinical toxicology

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                                                                             بسم الله الرحمن الرحيم                                              General laboratory findings in clinical toxicology 1 - Routine biochemical analysis : blood glucose, Electrolytes, blood       gases, pH, plasma enzyme and Cholinesterase activity. 2- Hematological analysis : hematocrit, blood clotting, leukocyte count. 3- Clinical toxicology analysis : therapeutic drugs and drugs of abuse 1-Biochemical tests: (a) Blood glucose   ● Marked hypoglycaemia often results from overdosage  with antidiabetic drugs.    ● Hypoglycaemia may also complicate severe poisoning with a     number of agents including iron salts and certain fungi.     ● Hyperglycaemia is a less common complication of poisoning than hypoglycaemia, but has been reported after overdosage with acetylsalicylic acid, salbutamol and theophylline (b) Electrolytes, blood gases and pH    ● Acid-base and electrolyte disturban

IDENTIFICATION OF FUNGI

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                                                                    بسم الله الرحمن الرحيم                                                                   IDENTIFICATION OF FUNGI Specimen collection Specimens for fungal microscopy and culture may be:  Scrapings of scale, after cleaning with alcohol.  Skin stripped off with adhesive tape, which is then stuck on a glass slide.  Hair which has been pulled out from the roots.  Brushings from an area of scaly scalp.  Specimens for fungal microscopy and culture may be:  Nail clippings.  Skin biopsy.  Moist swab from a mucosal surface (inside the mouth or vagina) in a special transport medium.  A swab should be taken from pustules in case of secondary bacterial infection.  Morphology Direct Microscopy  Potassium hydroxide (KOH) stained with blue or black ink.    Unstained wet-mount. Stained dried smear.  Histopathology of biopsy with special stains.  Types of fungi A.Molds (filamentous fu